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Dutta D, Bhattacharya S, Surana V, et al

Sulfonylureas (such as glipizide, glyburide, and glimepiride) also increase hypoglycemia risk when combined with semaglutide

Semaglutide begins activating GLP-1 receptors within 3060 minutes of injection, but appetite suppression typically peaks 13 hours post-injection and remains elevated for 7 days

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