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One older study found that small amounts of these compounds can pass through the skin from adhesive patches, but theres no evidence that this level of absorption translates into meaningful weight loss
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For instance, of 12 CALMs treated with a Q-switched ruby laser in one study, 50% developed repigmentation within 6 months
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These effects appeared across multiple IBS subtypes, with some of the strongest signals in IBS-C and mixed-type IBS
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