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While they appear to be well tolerated, these are powerful biological agents so its wise to proceed slowly and remain cautious
Brashears, M
Last reviewed: June 19, 2026 Last updated: June 19, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
The critical factor is that loading usually takes at least 2-3 months, so this is best timed to coincide with the start of serious building in training load towards a goal
Severe dehydration lowers blood volume and blood pressure, which reduces blood flow to the kidneys
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