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The pharmaceutical formulation according to any one of claims 1-9, further comprising a buffer having at least one pKa of about 5.0-7.0, such as citrate and/or histidine
Most people experience mild, temporary effectscooling or heaviness in the arm, small bruise or swelling at the IV site, brief fatigue, lightheadedness, headache, mild nausea, or a mineral/metallic taste
This prodrug is in ester form and then after absorption in the systemic circulation, this ester form of chloramphenicol undergoes hydrolysis and releases an active drug that is chloramphenicol
A novel and increasingly studied structure in this context is the primary cilium, a microtubule-based organelle that functions as a signaling hub for pathways including Sonic Hedgehog (Shh), Wnt/Wingless, and mechanistic target of rapamycin (mTOR)
It is mainly found in beef, fish and poultry
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