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Gastroenterology 142, 897906

It does not titrate up

Endotoxins and Detoxification Mechanisms Endotoxins are produced by certain bacteria in the gut, especially gram-negative bacteria, and can enter the bloodstream when the gut lining is compromised

Excess free iron (Fe2+) generates reactive oxygen species (ROS) through the Fenton reaction, causing lipid peroxidation of the membrane (144)

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