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The dose is usually increased every 4 weeks until the maintenance dose is reached: Weeks 1 to 4: 0.25mg once weekly Weeks 5 to 8: 0.5mg once weekly Weeks 9 to 12: 1.0mg once weekly Weeks 13 to 16: 1.7mg once weekly Week 17 and onwards: 2.4mg once weekly (maintenance dose) Your treatment provider may adjust this schedule depending on how well you tolerate the medicine

20 Dipeptidyl-peptidase-4 inhibitors are less potent in terms of lowering A1C (0.5% to 0.9%) and more expensive compared with other generically available agents

The dosage of retatrutide is still experimental and should be used as prescribed by your doctor

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