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Regional Disciplinary Medical Board: vitamin B12 cannot be overdosed In 2009, the Regional Disciplinary Medical Board in Eindhoven stated very clearly that an overdose is not possible: There can be no question of an overdose of hydroxocobalamin, as the excess is excreted in urine by the kidneys and therefore cannot accumulate in the body

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However, caution should be taken when extrapolating these results to the clinic

Light to moderate alcohol is usually fine, but heavy drinking can lower B12 levels and slow recovery