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When combined, the two treatments have been shown to result in fast and effective weight loss

The cost difference makes compounded semaglutide the de facto coverage workaround: For patients on Tier 4 plans or patients whose prior authorization was denied, compounded semaglutide is often less expensive than the post-insurance cost of brand Wegovy

Neither approaches the efficacy or tolerability of modern GLP-1 based treatments

Phase 3 clinical trial data showed average weight loss of 28.7% of body weight (approximately 71.2 pounds) at the 12 mg dose over 68 weeks