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There is limited evidence that prior cholecystectomy alters other risks associated with GLP-1 medications, and no specific UK contraindication exists

A prospective cohort study involving 266 elderly adults treated with epithalamin (the parent compound from which Epithalon was derived) over 2-3 years with subsequent 4-5 year follow-up demonstrated mortality reduction of 28% overall, with a 2-fold decrease in cardiovascular disease-specific mortality

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Having a professional evaluation before commencing treatment ensures safe usage

JAMA Netw Open 7, e2416578 (2024)