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The results of KEGG signaling pathway enrichment analysis showed that differential genes played an important role in platelet activation pathway, complement and coagulation cascades pathway, other glycan degradation pathway, other type of O-glycan biosynthesis pathway, cellular senescence pathway, cytokine-cytokine receptor interaction pathway, and apoptosis pathway
Decreased receptor sensitivity at target tissues has also been observed in some research contexts
Mutations in genes like PLA2G6 , involved in phospholipid hydrolysis, are linked to neurodegenerative diseases with brain iron accumulation, sharing features with PD (179)
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