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The stereochemistry at the 3-position determines biological activity, with only the L-isomer serving as substrate for carnitine palmitoyltransferases
doi: 10.1007/s42000-019-00144-2 70 ChatchomchuanWThewjitcharoenYKarndumriKPorramatikulSKrittiyawongSWanothayarojEet al
With that in mind, here is a realistic timeline for people who are correcting a genuine deficiency
These enzymes are strongly FAD-dependent, and mutations often destabilize FAD-binding motifs or enzyme complexes, impairing fatty acid -oxidation and energy homeostasis
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