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Another study has shown that developed germ cells, such as spermatozoa, are more susceptible to oxidative stress and ferroptosis than undeveloped germ cells [74]
This steep Ca 2+ gradient creates a strong driving force for Ca 2+ entry and is maintained by the low Ca 2+ permeability of the resting erythrocyte and high Ca 2+ -extruding capacity through a Ca 2+ ATPase and Na + /Ca 2+ exchanger in the cell membrane
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(2012) 2:e51
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