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The use of nalbuphine, a blocker of - and -opioid receptors, also disrupted the effect of GLP-1RAs on reducing TNF- levels, highlighting the essential role of these opioid receptors in the anti-inflammatory effects mediated by GLP-1RAs

As far as MCFG resistance is concerned, from our data it is not evident a role of glutathione metabolism in supporting this condition

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