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Patients with high-sensitivity variants may benefit from slower dose titration or closer monitoring, reducing stress on organs during the adaptation phase
A lot of it can be genetics
The enzyme dipeptidyl peptidase 4 (DPP4) is responsible for breaking down incretins
The inactive form is considered a precursor as it gets converted into an active peptide GLP-1 (7-37) by cleaving a single arginine residue (Fig
As you can see, there are a variety of other approaches
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