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2 GLP-1 is an incretin hormone produced by intestinal L cells that is responsible for up to 70% of insulin secretion in response to nutrient intake

Ipamorelin complements this process by stimulating growth hormone release through a separate receptor pathway

Bicalutamide (Casodex) in the treatment of prostate cancer: history of clinical development

They are generally avoided in people with a personal or family history of medullary thyroid cancer or MEN2 syndrome, a history of pancreatitis, severe gastroparesis, or during pregnancy and breastfeeding, and they require caution in significant kidney or liver disease

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