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Keeping it off is an identity change For decades the model was lifestyle first, with medication as the backup
Moreover, the peripheral and brain pools of 5-HT are synthesized separately and isolated from each other by the blood-brain-barrier
This redox imbalance leads to cross-linking of L-OOHs with macromolecular proteins essential for cellular functions, disruption of membrane integrity, and ultimately ferroptosis (Jin et al., 2024)
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