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Triple agonists are unimolecular peptide drugs that target GLP-1R, GIP receptor, and glucagone receptor, developed primarily for treating metabolic diseases (Knerr et al., 2022)
Remember that each persons body responds differently to these weight loss medications, and what works for one person may not work for another
Once this is achieved, the goal is to come off the medication while sustaining improvements through lifestyle interventions
For example, asymptomatic stones discovered during diagnostic imaging may not be treated, but an acute symptomatic kidney stone demands an intervention, even if only hydration and painkillers for a small stone (Curhan 2012
These effects may create a vicious cycle in which low-level inflammation promotes fungal colonization and fungal colonization promotes further inflammation
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