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Some 25 percent of people with MASH may go on to develop liver cirrhosis, permanent scarring that damages the organ, and liver cancer, both of which can cause organ failure

3 4 5 6 As of 2026, several medications are approved by health authorities specifically for chronic weight management

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Eli Lillys Zepbound, with the active ingredient tirzepatide, has been approved by the Food and Drug Administration for use by obese or overweight adults who have at least one weight-related health complication, like Type 2 diabetes, high blood pressure or high cholesterol