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Retatrutide Side Effects (What Trials Show) Clinical research on the retatrutide peptide shows a predictable pattern of side effects similar to GLP-1 and GIP agonists, with additional reactions linked to glucagon activation
Some individuals may require more than one vial per month
Ozempic and Wegovy are both once-weekly injections given in the subcutaneous area of the thighs, upper arm, or stomach: Ozempic comes as a multi-use pen and requires a new needle each time
Ozempic may cause fatigue in some individuals, particularly during the initial stages of treatment as the body adjusts, but this side effect is typically temporary and often resolves over time
