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Supplemental Figure 7
In parallel, AMPK can promote autophagy initiation (e.g., via ULK1 activation and mTORC1 restraint), providing a route for lipophagy and mobilization of lipid substrates that feed mitochondrial and peroxisomal oxidation (He et al., 2020)
Consideration of Alternative Dosages or Forms: Sometimes, adjusting the dosage of semaglutide or changing the form (such as switching from injection to oral medication if available) can help reduce skin reactions
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