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Mitochondrial Signaling & Metabolic Regulation MOTS-C is a mitochondria-derived peptide studied for effects on metabolic homeostasis , glucose utilization, and exercise-related signaling
Why to be leery of online claims The lack of conclusive clinical evidence regarding berberines potential weight-loss benefits is why, in 2022, Frontiers in Nutrition published a systematic review and meta-analysis of 49 studies and concluded that "although [berberine] may affect weight, it does not have a statistically significant and considerable effect" on body mass index
S1b, S1c)
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