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In addition, SGLT-2 inhibitors have shown benefit in patients with both HFrEF and HFpEF independently of diabetes status, which opens exciting possibilities for the use of these therapies in patients at risk for or with established CV or kidney disease without T2D

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However, -endorphin-neutralizing antibodies did not affect morroniside-induced IL-10 expression, indicating that IL-10 acts upstream of -endorphin in this signaling cascade [74]

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Q: Should I stop taking tirzepatide if I get a rash