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Usually resolves within hours
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2 hrs after reaching the maximum plasmatic concentration, the concentration of active drug is higher in the synovial fluid than in the plasma and the rest is reached in a period of 12 hrs
However, if serum cobalamin concentration is within the normal range, treatment should be continued at least monthly and the owner should be forewarned that clinical signs may recur sometime in the future
If necessary, a bandage may be applied to the site
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