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This warning is based on studies in rodents, and the actual risk in humans is still being investigated

W.LawitzE.BugianesiE.et al (2024)

This is the foundational selectivity paper

Practically, this is why it is often chosen for routines focused on visible recovery and resilience, especially when skin feels stressed or compromised

DSIP significantly increased the rate of phosphorylated respiration (V3), which represents the maximal oxygen consumption rate in the presence of ADP