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1997;156(2 Pt 1):425-430

Cardiovascular and other outcomes Semaglutide is approved by the FDA for reducing the risk of major adverse cardiovascular events (MACE) in adults with type 2 diabetes and those with diagnosed heart disease

Designed for patients who want to improve energy and burn fat (metabolic fitness) while using GLP-1s only as a background support tool to avoid muscle loss or severe side effects

Holt, PharmD, BCPS, an assistant professor of Pharmacology at PCOM South Georgia, answers some of these questions

Some people carry variants that enhance GIP-receptor responsiveness, suggesting tirzepatide may be particularly effective