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Free Radic Biol Med 21 : 157161

The theory is that cycling prevents receptor desensitization and reduces cumulative side effect burden

Penney et al., 2020)

Whilst these medications offer significant therapeutic benefits, gastrointestinal side effectsincluding acid reflux and heartburnare commonly reported

Topical cream protocols Topical formulations allow targeted delivery to skin wounds, burns, and localized inflammation