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This reacts with nitric oxide to produce peroxynitrite, which requires iron (released from lysosomes) to catalyze the formation of nitrotyrosine adducts on proteins, leading to induction of the MPT and ultimately cell necrosis
What this article covers is the biological reasoning behind timing considerations the mechanisms that inform why injection timing matters and what factors are worth discussing with your provider
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For patients without thymoma, if the patient is AChR antibody-positive and has early-onset disease, thymectomy is also available as a treatment to improve symptoms
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