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But several situations make it especially reasonable
This means that not only is this treatment effective, it is also becoming more accessible to those looking to improve their health and wellbeing
Because it competes at the nicotinamide substrate site rather than the SAM cofactor site, it is also used as the substrate-competitive reference compound against which bisubstrate and covalent NNMT inhibitors are benchmarked
Most patients need a customized dosage plan based on the severity of the deficiency and nerve symptoms
Patients taking metformin, those with gastrointestinal symptoms, older adults, or those with restricted diets should discuss B12 monitoring and potential supplementation with their GP
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