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doi: 10.3389/fphys.2026.1826699 Received 09 March 2026 Revised 02 April 2026 Accepted 09 April 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Satoko Shinjo, University of Padua, Italy Reviewed by Alejandra Tomas, Imperial College London, United Kingdom Emily Walker, Wayne State University, United States Updates Copyright 2026 Cruz, Puebla-Huerta, Troncoso, Silva-Pavez, Hidalgo-Fadic and Ahumada-Castro
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Limitations of Use: Compounded semaglutide should not be used in combination with other semaglutide-containing products or any other GLP-1 receptor agonist The safety and efficacy of coadministration with other products for weight loss have not been established Compounded semaglutide has not been studied in patients with a history of pancreatitis Note: Compounded medications are not FDA approved and do not have indications for treatment as an FDA approved medication would
It recommends weighing "the benefits of breastfeeding for the child and the benefits of treatment for the mother" along with any potential risks
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