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Enzyme-linked immunosorbent assay (ELISA) ELISA assay kits were procured from Elabscience (Wuhan, China) and Enzyme Link Biotechnology (Shanghai, China)

Weight Loss Maintained After Stopping Semaglutide Small Numbers After 26, 64, and 76 weeks, a total of 1,392, 359, and 185 participants remained in the program, respectively (median overall follow-up time was 32 weeks for the 2246 individuals who started the program)

Subcutaneous injection distributes the peptide systemically, meaning it can affect skin throughout the body rather than only where directly applied

There is no established link between retatrutide and serious long-term fatigue disorders, but all persistent or unexplained symptoms deserve thorough clinical evaluation

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