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Es recomendable un control glucmico ms estrecho durante las primeras semanas tras la sustitucin.
PLoS One 1, e79 (2006)
14 GLP-1 (736) NH 2 , exenatide (128) and GIP (130), all have two polar residues starting from position 27: GLP-1 has Lys 28 and Arg 30 , exenatide has Lys 27 and Asn 28 , and GIP has Gln 29 and Lys 30
Horvth JE, Groot K, Schally AV
The culture was initially run in batch-culture mode until ~6 h after the exhaustion of the carbon source as determined by continuous and automated monitoring of the oxygen saturation within the culture vessel every 10 s
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