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Clinical trials such as SURMOUNT-1 have demonstrated average weight loss of 15-21% of body weight over 72 weeks (depending on dose), with much of this effect attributed to reduced caloric intake
Implications for diabetes treatment While GLP-1 is typically made in the gut, the study confirms that alpha cells in the pancreas can also release GLP-1into the bloodstream after eating, helping to lower blood sugar by increasing insulin and reducing glucagon levels
Although Semaglutide GLP-1 starts acting soon after injection, most people dont notice significant effects immediately
Serious but Rare Side Effects Serious side effects are uncommon but can include inflammation of the pancreas, severe digestive issues, gallbladder problems, kidney injury from dehydration, low blood sugar (hypoglycemia), serious allergic reactions, and vision changes in patients with type 2 diabetes
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![PDF] Tirzepatide-Induced Injection Site Reaction](https://figures.semanticscholar.org/18fb0b8dbc04c04a7b5177d9fd87256fc7c060bb/2-Figure1-1.png)
