retatrutide triple agonist glp-1 gip glucagon receptors Obesity Targeting 💉 A triple-action once-weekly injection

some randomized controlled trials demonstrated that liraglutide, dulaglutide, semaglutide, and albiglutide reduced the rate of CV events in T2DM patients ( Another novel glucose-lowering agent is tirzepatide which has a dual mechanism of action: a GLP-1 and a glucose-dependent insulinotropic polypeptide (GIP) co-agonist

Obstructive Sleep Apnea

The transport of ADP and ATP across the inner mitochondrial membrane occurs through the action of the ADP/ATP carriers (AAC) which are typical antiporters

The patients in the STEP-HFpEF DM trial saw statistically significant improvements in 6MWT distance and quality of life, as well as reductions in HbA 1c level

Suppresses appetite (central action): Reduces hunger signals in the brain, leading to decreased food intake and weight loss 1,2