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It also helps to regulate the production of pigment in the skin, meaning that you will have a more even skin tone and fewer dark spots

One of the main molecular pathologic mechanisms in this setting is represented by -synuclein aggregation in mitochondria, which leads to the production of reactive oxygen species (ROS) and induces activation of p38 MAPK, a MAP-kinase that triggers the phosphorylation of Drp1 (dynamin-related protein-1), which eventually leads to mitochondrial fission ( Therefore, both T2DM and PD show strong connections between mitochondrial damage and increased oxidative stress, resulting in altered insulin secretion in the former case, and in neuronal damage and neuroinflammation in the latter

Journal of Cosmetic Dermatology 20(9):2793-2803

For the research community this means that clinical doses and durations are not validated , most of todays research protocols rely on animal models and hypothetical extrapolations