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A separate 2019 study in older mice reported that NNMT inhibition was associated with how muscle stem cells supported regeneration in rodent models a different research angle from the metabolic work
It did not cause the water retention or joint issues that plague growth hormone users
In fact, its been found that B12 supplements taken orally are just as effective as intramuscular shots in overcoming states of deficiency when you take up to 1,000 micrograms a day
Regular injections ensure that levels remain stable, whereas infrequent injections may result in declining B12 levels over time
For others, with milder or temporary deficiencies, the initial shots might lead to longer periods of feeling well, potentially even allowing for a switch to oral supplements under strict medical guidance
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