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By directly donating an electron to these dangerous compoundssuch as hydrogen peroxide, superoxide anions, and hydroxyl radicalsglutathione effectively neutralizes them before they can inflict structural damage on the cell
Copper toxicity, oxidative stress, and antioxidant nutrients
L., Rateri, D
8 (download XLSX Statistical Source Data
So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations
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