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Vehicle-treated Gipr fl/fl and Gipr Syn/ mice showed a 1.5% and 2.6% weight gain, respectively, whereas mGIPR-Ab/P1-treated Gipr fl/fl mice lost 20% of their body weight (Fig

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Shingles occurs due to the reactivation of the varicella-zoster virus (VZV) , which remains dormant in nerve cells after a person has had chickenpox

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By targeting all three pathways, these compounds may achieve greater metabolic effects than single or dual agonists

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