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However, B12 supplementation is not directly associated with weight loss

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When HbA1c is considered unreliable for example, due to B12 deficiency or anaemia UK and WHO guidance recommends using a fasting plasma glucose test or a 75 g oral glucose tolerance test (OGTT) for diabetes diagnosis or assessment

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The Prohibited List (S0 Non-Approved Substances

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Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal [lower than normal], further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly

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It should be noted that parenteral choline, inositol, and methionine combinations are not licensed medicines in the UK

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