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these findings suggest that tumor regression in response to chemotherapy was correlated with the inhibition of GPx1 activity and confirmed the role of GPx1 in the occurrence and development of breast cancer (Fig

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7.2.1 Priorities for clinical studies Large-scale, long-duration randomized controlled trials (RCTs) are urgently needed to evaluate how emerging combination therapies impact hard renal endpoints, including serum creatinine doubling, progression to kidney failure, and renal death

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