Winning DoD R&D Funding: SBIR, BAAs, OTAs, and the Opportunities Most Companies Miss The Department of Defense invests billions of dollars in research and development each year ($141.2B in FY2025) and a significant share of that flows directly to private industry
Chronic inflammation is probably the biggest driver, whether from gut infections like SIBO or candida, autoimmune conditions, or persistent immune activation
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In preclinical models, BPC157 has been shown to modulate expression of key inflammatory mediators by downregulating proinflammatory transcription factors such as NFB and AP1 while upregulating antiinflammatory genes linked to IL10 signaling, thereby shifting the balance toward resolution of inflammation in chronically injured tissues (24,25)