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ELISA-based assay for biomarkers ELISA measurements from plasma samples were carried out using the Ciraplex platform (Aushon Biosystems, Billerica, MA, US)

For patients managing glutathione refills at home, the gap between effective supplementation and wasted product comes down to three logistics most guides never mention: reconstitution timing, refrigeration discipline, and reorder cadence

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The most common effects were nausea, vomiting and abdominal pain

More widespread use of SGLT2i in type 1 diabetes will necessitate implementation of strategies to assess and mitigate DKA risk, including preventative measures, patient education and continuous ketone monitoring, as well as a better understanding of the potential benefits for clinical cardiorenal outcomes, especially in high-risk populations such as people with CKD (Table 2) [46, 47]