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10.1177/20587384211059675 198 MatthayM
While Yuans recent study confirmed the efficacy of GLP-1RAs, the researchers also found that some patients did experience adverse side effects, especially related to gastrointestinal issues like nausea and vomiting
Because of their opposite functions on food intake and metabolic targets (Engelstoft & Schwartz, 2016), both hormones have gained traction as pharmacological targets for treatment of metabolic (i.e., obesity and type 2 diabetes (T2D)) and eating disorders (Atalayer et al., 2013
While often uncomfortable, it's important to distinguish normal side effects from warning signs of more serious conditions like pancreatitis or gallbladder disease, which require prompt medical attention
Treatment with semaglutide improved outcomes in both heart failure with reduced ejection fraction and heart failure with preserved ejection fraction groups [39], suggesting broad cardiovascular protective effects across different phenotypes of heart disease
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