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Front Cell Infect Microbiol

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They are not FDA-approved drugs that undergo the same rigorous mass-manufacturing testing

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2.3 Comparison of selective versus dual PDE1B/PDE10A inhibition Selective inhibition of PDE1B or PDE10A enabled targeted modulation of distinct intracellular signaling cascades

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10.1038/npp.2013.121 39

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Tendons and ligaments take longer: Structural repair of tendon and ligament tissue takes months, not weeks

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