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00:26:04 Jennifer Trujillo I dont feel like I have a great answer because I do feel like we talk about it in clinical practice, but Im not completely convinced that its due to something like GLP-1 receptor downregulation or something like that
In human cell culture studies, increased expressions of PAI-1 and VCAM-1 have been reported to be associated with hyperglycemia-related endothelial cell dysfunction, a process that predisposes vasculature to accelerated atherogenesis 52
Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: A systematic review and meta-analysis of randomised trials
The clinical significance and potential therapeutic role of GPx3 in tumor recurrence after liver transplantation
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