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Supports keratin production Biotin is crucial for the production of keratin , the protein that makes up the structure of hair, skin, and nails
One significant limitation is its half-life, which is approximately 90 minutes
While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population
We outline major translational and biological challenges, identify key gaps for future research and discuss emerging approaches aimed at achieving durable and scalable obesity treatment
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