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The dual action on both GIP and GLP-1 receptors contributes to the significant weight loss observed in clinical trials
The primary outcome was change in HbA1c values from baseline to 24 weeks, whereas secondary endpoints were changes in HbA1c and weight after 36 weeks (Table 1) [4]
Maintenance: Dose may be increased in increments of 2.5 mg every 4 weeks as needed
10.1016/j.foodchem.2024.139637 117 XuY.MinhazulK
The primary endpoints include the proportion of patients with resolution of NASH without worsening of fibrosis and a composite long-term outcome (all-cause mortality, cirrhosis and liver-related clinical outcomes) at 72 weeks with estimated follow-up of 4 years
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