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: Direct stimulation of 1 -Adrenergic Activation 1 -adrenergic receptors on myocytes increases myocardial chronotropy (heart rate) and inotropy (contractile force), thereby elevating or maintaining cardiac output (CO), depending on the dose used (Solanki et al, 2014)

Nov-Dec 01 2022;29(6):e637-e643

doi: 10.1038/s41467-025-57152-7 237 LiY.et al

The peptide therapy community relies heavily on animal model data when discussing potential applications, but this creates significant gaps in understanding human safety, dosing, and effectiveness

The study population offers some unique opportunity to explore whether genes can provide protection to a specific disease-related environmental exposure