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In addition to activating GLP-1 receptors, it also targets GIP receptors

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Important safety considerations include: Gastrointestinal symptoms at higher doses Individual tolerance variability Potential for hypoglycaemia when combined with insulin or sulphonylureas Limited long-term safety data in humans Limited data in children and adolescents Patients with diabetes taking glucose-lowering medications should exercise caution when introducing allulose

At the endpoint, mice were euthanized and blood, spleen, kidney, liver and lung were collected and snap-frozen until further analysis

Then add an appropriate amount of lithium aluminum hydride hydrochloride and ethylene glycol solution to complete the cyclization reaction