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however, these factors would affect all groups equally and do not invalidate between-group comparisons

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110,111 Causes of ER expression loss include epigenetic regulation, hypoxia, overexpression of epidermal growth factor receptor (EGFR) or human epidermal growth factor receptor 2 (HER2), and dysregulation of tumor suppressors such as p53 and pRb2/p130

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Muscle mass change in the untreated leg accounted for only 9%

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