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Merrifield conceived of SPPS in 1959 and took four years to demonstrate the synthesis of a simple tetrapeptide, in a sole-authored Journal of the American Chemical Society (JACS) paper [20] that became among the journals most-ever cited

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This once-daily treatment consists of dissolving your medication on the side of your cheek/mouth and has been proven to significantly reduce common side effects, such as nausea and stomach pain, experienced with injections